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New paper in collaboration with Pavlinkova lab published this week in PNAS

ISL1 is necessary for auditory neuron development and contributes toward tonotopic organization



Invited lecture at 1st 10X Genomics experience meeting 2022

Lukas Valihrach and Daniel Zucha gave a talk on spatial transcriptomic analysis in experimental model of ischemic brain injury



New paper about RNA localization

Our laboratory published new study: Evolutionary conservation of maternal RNA localization in fishes and amphibians revealed by TOMO-Seq



New paper!

Transcriptome and Proteome Analyses Reveal Stage-Specific DNA Damage Response in Embryos of Sturgeon (Acipenser ruthenus)



New paper published with our favorite collaborator and friend Agnieszka

Obesity Affects the Proliferative Potential of Equine Endometrial Progenitor Cells and Modulates Their Molecular Phenotype Associated with Mitochondrial Metabolism.



New paper published in Frontiers in Cell and Developmental Biology

Isolation and Characterization of Highly Pure Type A Spermatogonia From Sterlet (Acipenser ruthenus) Using Flow-Cytometric Cell Sorting



New collaboration project funded by Czech Science Foundation

The role of Meis transcription factors in mesenchymal condensations during formation of the cranium.



Alexander disease: an ultra-rare neurodegenerative disease

Short description of Alexander disease and announcement of our recent project focused on its characterization



Tutorial: Guidelines for Single-Cell RT-qPCR.

Secrets of single-cell RT-qPCR revealed in our recent publication!



Lukas Valihrach invited to talk at 7th European Stroke Conference

Interaction of Aging and Stroke on Cellular and Molecular Level – Implications for Stroke Treatment



Our new paper published in Glia

Transient astrocyte-like NG2 glia subpopulation emerges solely following permanent brain ischemia



Two-tailed RT-qPCR in Covid-19 diagnostics and prognostics!

New test can reveal whether there is a danger of a serious clinical course of Covid-19.



The untold story of 10x Visium Transcriptomics: our hands-on experience

Webinar by Daniel Zucha for 10x Genomics



Master and bachelor theses successfully defended.

Congratulation to Paulina and Jirka!!!



Small RNA-Sequencing: Approaches and Considerations for miRNA Analysis

Our new review published!



Small RNA-sequencing for Analysis of Circulating miRNAs: Benchmark Study

Preprint



Monitoring of serum biomarkers in patients with acute spinal cord injury

Our new project funded by Czech health research council



Two papers published in collaboration with LabGenEx!

Ancient Sturgeons Possess Effective DNA Repair Mechanisms: Influence of Model Genotoxicants on Embryo Development of Sterlet, Acipenser ruthenus and Novel technique for definite blastomere inhibition and distribution of maternal RNA in sterlet Acipenser ruthenus embryo.



We've got new funding for next 5 years!

GIPTSAL - Globalization, modern technologies and climate change provide both new opportunities and hazards for salmonid breeding management.



Cautionary note on contamination of reagents used for molecular detection of SARS-CoV-2.

New publication in Clinical Chemistry published in collaboration with Laboratory of Gene Expression.