Lukáš Valihrach, PhD
I am a researcher in Kubista lab where I am interested in utilizing different tools for single cell gene expression analysis, especially using RT-qPCR and RNA-Seq. My research is focused on characterization of glial cells (especially astrocytes, NG2 cells, microglia) in different pathophysiological conditions - after ischemic brain injury or in the progression of neurodegenerative diseases (Alzheimer’s disease, amyotrophic lateral sclerosis). I am also interested in new method development and their application in interesting models, e.g. role of microRNAs and their application as biomarkers in patients with acute spinal cord injury. I collaborate with several laboratories, mainly from Institute of Experimental Medicine, using most current approaches for gene expression analysis in the field (their implementation is an important part of my work). I received my PhD at University of Chemistry and Technology in Prague and spent few months as an intern in Denmark and Sweden. In addition to research, I enjoy training young students and learning new things. When not in lab, I love running in the mountains, partying with friends, and hanging out with my overactive dog.