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Addressing biological heterogeneity with single cell profiling



Kubista, M. Addressing biological heterogeneity with single cell profiling. European Pharmaceutical Review, 20(3): In-depth focus: PCR, 2015.

Abstract

The more we study biology, the more complexity we discover. Organs, for example, are composed of many different cell types and several tumour types are thought to be polyclonal. It is the individual cells that make up tissues and organs that we need to study in order to better understand biological responses and communications, and during the past few years we have seen important developments in techniques for single cell profiling and in methods to analyse such data.