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Unrevealing biological secrets by single cell expression profilig



Stahlberg, A., Kubista, M. Unrevealing biological secrets by single cell expression profilig. Drug Discovery World Summer, 2013.

Abstract

During the last 30 years exceedingly sensitive and accurate technologies have been developed to measure and quantify amounts of nucleic acids and proteins. With techniques such as quantitative real-time PCR (qPCR) and nextgeneration sequencing (NGS) DNA, messenger RNAs (mRNA), micro RNAs (miRNA), long non-coding RNAs (lncRNA) and today even proteins can be measured in most types of samples allowing the comparison of environmental conditions, studies of diseases and monitoring of treatments.